| Product Name |
Cycloastragenol |
| CAS |
84605-18-5 |
| MF |
C30H50O5 |
MW
|
490.71 |
EINECS
|
N/A |
Cycloastragenol (TA-65), a small-triterpenoid purified from the root of an Asian medicinal herb, has currently received particular attention for its potential to regulate transcription of telomerase. TA-65 is capable to increase average telomere length and to decrease the percentage of critically short telomeres and DNA damage in MEFs that harbor critically short telomeres. The effects on telomerase appear to be in common with other triterpenoid saponins (ie, ginsenosides RG1 and Rg3). These compounds at concentrations from 1 to 20 μM were reported to protect against IL-1β-, H2O2-, and tert-butylhydroperoxide-induced senescence in human chondrocytes, endothelial progenitor cells and fibroblasts, respectively.
Cycloastragenol, the aglycone derivative of astragaloside A, can be found in various species of Astragalus and is reported to activate telomerase. It has been shown to slow telomere loss, increase replicative capacity, and improve immune function in CD8+ T lymphocytes from HIV-1-infected patients.
Q:How to order a sample for quality testing purpose before your commercial order?
A: We do provide our clients small sample for quality testing purpose (Sample size form 1-50 grams). Free samples can be provided for some products due to the material cost, Our clients only need to pay the international shipping cost or provide us your Fedex/DHL account number so we can arrange the shipments. so please contact us in details by email.
Q: How to start orders or make payments?
A: You can send us your Purchase order(PO), or just send a simple confirmation by email, after communication then we will send you Proforma Invoice with our bank details for final confirmation, then you can make payment accordingly.
Q: What's our Minimun Ordering Quantity (MOQ)?
A: For the high value products, our MOQ starts from 1 gram and other products generally starts from 1 kilogram. For other low value products, MOQ can be started from 10kgs to 100kgs.
Q: Is there a discount?
A: Yes, we offer lower prices for larger quantities. There will be difference prices range on our quotation list so please inform us what quantity you will be after.
Q: How do we guarantee our products quality?
A: First of all, our quality control system will reduce our quality problem to near zero.We can always provide our certificate of analysis according to every batch of our products.We can also provide third party analysis testing due to our clients' requirement.
If there is any quality issue caused by us, we will send you free goods for replacement or refund your loss.
Q: How to contact us ?
A: You can contact us thought inquiries to message box of any of our products displayed or sent us emails to our company email address or simply call us at anytime!
Audited Supplier 
){kind=link}
){kind=link}