Factory Supply Pharmaceutical Intermediate CAS 153851-71-9 Biopenem Side Chain

• CAS No.: 153851-71-9
• Formula: C5h8cln3s
• EINECS: 604-929-8
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Technical
• Colour: White
• Transport Package: 1kg/Carton, 25kg/Drum
• Specification: NLT98%
• Origin: Shandong
• Production Capacity: 1000kg/Month

Product Description

 

Product Description

 
Biapenem side chain is a pharmaceutical raw material that can be used to produce Biapenem antibiotics.  Biapenem (LJC 10627) is a carbapenem antibiotic for injection.  The most significant feature of this product is that the S in 2-position has bicyclic triazole 1β-methyl carbapenem.  The study of structure-activity relationship shows that the presence of the side chain quaternary ammonium cation center is the key to affect the permeability of the outer membrane, so that its ability to inhibit the activity of pseudomonas aeruginosa and anaerobic bacteria is 2~4 times that of imipenem,  its ability to inhibit the activity of drug-resistant pseudomonas aeruginosa is 4 to 8 times that of Meropenem, and its effect on acinetobacter and anaerobic bacteria is more effective than ceftazidime.
 

Product Name	Biopenem Side Chain
CAS	153851-71-9
Appearance	White powder
MF	C5H8ClN3S
MW	177.66
Melting Point	127-128 °C
Storage	2-8°C
Structural Formula

 

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