| Product Name |
ISRIB (trans-isoMer) |
| CAS |
1597403-47-8 |
| MF |
C22H24Cl2N2O4 |
MW
|
451.34 |
EINECS
|
N/A |
ISRIB (integrated stress response inhibitor) as a drug, imparts resistance to the cells against the downstream effects of eukaryotic initiation factor 2 (eIF2)α phosphorylation such as activating transcription factor 4 (ATF4) and eukaryotic translation initiation factor 4E (eIF4E)-binding protein 1 (4E-BP1) induction.
ISRIB is a blood- brain barrier penetrant, potent and selective inhibitor of integrated stress response (ISR) that impairs adaptation to ER stress. ISRIB is a potent inhibitor of PERK signaling, which potently reverses the effects of eIF2a phosphorylation and restores the cells translation capacity. ISRIB enhances cognitive memory in rodents.
Q:How to order a sample for quality testing purpose before your commercial order?
A: We do provide our clients small sample for quality testing purpose (Sample size form 1-50 grams). Free samples can be provided for some products due to the material cost, Our clients only need to pay the international shipping cost or provide us your Fedex/DHL account number so we can arrange the shipments. so please contact us in details by email.
Q: How to start orders or make payments?
A: You can send us your Purchase order(PO), or just send a simple confirmation by email, after communication then we will send you Proforma Invoice with our bank details for final confirmation, then you can make payment accordingly.
Q: What's our Minimun Ordering Quantity (MOQ)?
A: For the high value products, our MOQ starts from 1 gram and other products generally starts from 1 kilogram. For other low value products, MOQ can be started from 10kgs to 100kgs.
Q: Is there a discount?
A: Yes, we offer lower prices for larger quantities. There will be difference prices range on our quotation list so please inform us what quantity you will be after.
Q: How do we guarantee our products quality?
A: First of all, our quality control system will reduce our quality problem to near zero.We can always provide our certificate of analysis according to every batch of our products.We can also provide third party analysis testing due to our clients' requirement.
If there is any quality issue caused by us, we will send you free goods for replacement or refund your loss.
Q: How to contact us ?
A: You can contact us thought inquiries to message box of any of our products displayed or sent us emails to our company email address or simply call us at anytime!
Audited Supplier 
){kind=link}
){kind=link}